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All eyes on data on Biogen’s tau therapy

Biogen’s experimental anti-tau therapy, Diranersen, reports slowed cognitive decline in early Alzheimer's disease patients during Phase 2 clinical trials.

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The brief

Biogen presented Phase 2 CELIA study results at the Alzheimer’s Association International Conference (AAIC). The data indicates that the investigational anti-tau oligonucleotide, Diranersen, achieved robust tau reduction and slowed cognitive decline in individuals with early-stage Alzheimer’s disease.

Coverage from STAT, Fierce Biotech, AP News, and Biogen highlights that the observed rates of cognitive slowing are comparable to currently approved Alzheimer's therapies. Reports emphasize the significance of the data as the pharmaceutical industry seeks new therapeutic approaches for the condition.

Future updates are expected to center on the drug's path toward a pivotal development push. Coverage does not yet specify a timeline for further regulatory filings or late-stage trial designs.

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Quick answers

What is the name of the drug being studied?

The experimental anti-tau oligonucleotide is called Diranersen.

Where were these findings presented?

The results were presented at the Alzheimer’s Association International Conference (AAIC).

How does the drug's performance compare to existing options?

According to STAT, the drug slowed cognitive decline at rates on par with therapies that are already approved.

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