A pioneering figure in bioorganic and biological chemistry, Andrée Marquet, has died, leaving behind a lasting legacy of scientific advancement, and mentorship. Her work bridged the gap between chemistry and biology, influencing generations of researchers and students.
Marquet began her career at the CNRS after completing her studies at the École Nationale Supérieure de Chimie de Paris and earning her doctorate at the Collège de France. In 1978, she was appointed Professor at Pierre and Marie Curie University, where she founded a laboratory dedicated to biological organic chemistry. This laboratory evolved over the years into the UMR 7613 (Synthesis, Structure and Function of Bioactive Molecules), then the UMR 7203 (Laboratory of Biomolecules), and most recently the UMR 8228 (Physical Chemistry and Chemistry of Living Organisms). Her research program continues through a dedicated community of researchers and educators who share her passion for the intersection of chemistry and biology.
Marquet’s research focused on mechanistic enzymology, specifically the biosynthesis of steroids, vitamin K, and biotin. Though, her impact extended beyond specific research themes. She is remembered for fostering a novel way of thinking, bringing reactivity and mechanisms to the field of biochemistry and grounding organic chemistry in the complexities of living systems. This approach enabled communication and collaboration between previously distinct scientific communities.
Throughout her career, Marquet actively contributed to the advancement of chemistry through numerous scientific and institutional roles. She held leadership positions within the Société Chimique de France and the Maison de la Chimie, as well as at the CNRS and the Ministry of National Education, Higher Education and Research. Her dedication to scientific progress and education has left an indelible mark on the field.
Colleagues and former students remember Marquet as a deeply inspiring mentor. Condolences have been extended to her family and loved ones. Her contributions to understanding the fundamental processes of life will continue to resonate within the scientific community for years to reach.
