A deficiency in a key hormone may elevate the risk of Alzheimer’s disease, according to recent findings discussed by experts. This connection highlights the importance of understanding the role of hormones in cognitive health and potential preventative measures.
On February 18, 2026, popular lecturer Kim Mi-kyung spoke with Dr. Ahn Cheol-woo, a professor of endocrinology at Gangnam Severance Hospital, on her YouTube channel to discuss the hormone oxytocin. Dr. Ahn identified oxytocin as a crucial hormone for modern individuals, explaining that it is replenished through interactions with others.
“If oxytocin is deficient, it is easy to become socially isolated and feel lonely,” Dr. Ahn stated. He further explained that oxytocin influences the production and removal of amyloid proteins, potentially increasing the risk of impaired brain cognitive function and Alzheimer’s disease.
The most vital way to increase oxytocin levels, according to Dr. Ahn, is through “relationships and physical contact with loved ones.” He added, “A warm phone call or a word of comfort can also aid, and it is necessary to break out of isolation and engage in hobbies with others.”
Oxytocin is produced in the hypothalamus and stored and secreted in the posterior pituitary gland, acting as a neurotransmitter in the brain. It is primarily known for mediating social bonding, emotions, and stress responses.
The link between oxytocin and Alzheimer’s disease has also been the subject of research. A study by Maria Clara Celes’ team, published in the 26th volume, 4th issue of iScience, found that oxytocin expression in the hypothalamus decreases in Alzheimer’s disease models. The study also noted that administering oxytocin through the nasal cavity can stimulate oxytocin production within the hypothalamus.
Oxytocin deficiency is also associated with schizophrenia and autism spectrum disorder, further emphasizing its significance. The findings underscore the growing recognition of oxytocin’s broad impact on neurological and psychological well-being.
