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Most IVF ‘add-on’ treatments have no effect on fertility or remain unproven, study says

IVF ‘add-ons’—from supplements to procedures—face growing scrutiny as new research finds most lack proven fertility benefits

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The brief

A major review published in *The Lancet* concludes that the vast majority of complementary treatments marketed to IVF patients—such as acupuncture, nutritional supplements, and specialized lab procedures—have **no demonstrated effect on pregnancy rates** or remain unproven. Coverage highlights how these ‘add-ons’ are widely promoted despite limited scientific backing, with some clinics offering them as optional upgrades to standard IVF protocols. Outlets including *The New York Times*, *The Guardian*, and *The Sydney Morning Herald* note that patients—often desperate for higher success rates—are frequently pressured into purchasing add-ons with unclear benefits.

The *Science Media Centre España* and *India Today* frame the findings as a call for stricter regulation and transparency in fertility clinics. What to watch next: Regulatory bodies may tighten guidelines on IVF marketing practices, and clinics could face increased scrutiny over how they advertise unproven treatments. Patient advocacy groups may push for clearer disclaimers, while fertility specialists could see a shift in industry standards—though no immediate policy changes have been announced.

Coverage does not yet specify whether insurers will adjust coverage for these treatments.

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Quick answers

What are ‘IVF add-ons’?

Complementary treatments marketed alongside standard IVF procedures, such as acupuncture, nutritional supplements, specialized embryo culture media, or genetic testing upgrades. These are often sold as ways to improve pregnancy chances but lack robust clinical evidence.

Are these treatments banned or restricted?

No. The review does not call for bans, but it raises concerns about **misleading marketing**. Clinics can still offer add-ons, but patients may lack full transparency about their efficacy. Coverage suggests regulatory scrutiny could increase, but no outright prohibitions have been announced.

Which countries are most affected?

Australia and Spain have seen significant local coverage, with research highlighting high usage rates. The *Lancet* review’s findings are global, but regional differences in clinic practices and regulations may influence how quickly changes occur.

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