As the global population ages, research into strategies for healthy aging is gaining momentum. A new report from the Spanish Society of Anti-Aging and Longevity Medicine identifies five nutrients-resveratrol, quercetin, vitamins B3 & D, and glycine-showing promising potential in preventing chronic disease and improving quality of life, though experts caution against seeking singular solutions. While findings largely stem from preliminary studies, the report details how these compounds may impact key aging processes and offers a focused look at their observed effects on metabolic and cellular health.
Growing global interest in extending lifespan and improving health has fueled research into the role of nutrition in the aging process. A recent report, backed by the Spanish Society of Anti-Aging and Longevity Medicine, has identified five nutrients with the most scientific support for their potential to prevent chronic diseases and enhance quality of life. While much of the evidence comes from animal studies, early human trials are offering encouraging insights into how targeted nutrition may influence aging.
Resveratrol, a polyphenol found in grapes and berries, is among the nutrients highlighted for its antioxidant, anti-inflammatory, and immunomodulatory properties. Researchers have observed that resveratrol can improve factors like cholesterol levels, glucose metabolism, and endothelial function, but conclusive evidence demonstrating lifespan extension in humans remains elusive. Its effects are thought to be linked to the activation of sirtuins, but clinical trials have yielded variable results, and there is currently no consensus on the optimal dosage.
Quercetin, a flavonoid abundant in onions, apples, and citrus fruits, also shows promise. It functions as both an antioxidant and an anti-inflammatory agent, and notably exhibits senolytic effects – meaning it helps clear away aging cells. Studies in humans have shown reductions in blood pressure, cholesterol, and senescent cells, particularly in individuals with diabetes, and its potential impact on age-related diseases is under investigation. This research is particularly important as the global population ages and the prevalence of chronic conditions rises.
Vitamins B3 and its derivatives, including nicotinamide riboside and nicotinamide mononucleotide, play a crucial role in the production of NAD+, a coenzyme essential for energy metabolism and DNA repair. Supplementation with these compounds has demonstrated improvements in blood pressure, energy levels, and body composition in human trials, with no significant adverse effects reported.
Vitamin D, vital for bone, muscle, and immune health, is another key nutrient identified in the report. Deficiency is common, especially among older adults. Finally, glycine, an amino acid found in meat and fish, has shown benefits in animal models regarding longevity, cardiovascular function, and cellular energy, particularly when combined with N-acetyl-cysteine.
Experts emphasize that these nutrients should be incorporated into a balanced diet and tailored to individual needs. The report underscores the importance of a holistic approach to nutrition and healthy aging, rather than relying on single “magic bullet” solutions.
With information from Infobae
