As diagnoses of autism spectrum disorder and attention-deficit/hyperactivity disorder continue to rise, new research is exploring potential environmental links to these neurodevelopmental conditions. A study from Rowan University and Rutgers University suggests children with autism or ADHD may have reduced efficiency in eliminating bisphenol A (BPA), a common chemical found in plastics [[1]]. The findings, published in *PLOS one*, don’t establish causation but offer new insight into the complex factors that may contribute to these disorders.
Rising diagnoses of autism and attention-deficit/hyperactivity disorder (ADHD) over recent decades have prompted researchers to investigate potential contributing factors. A new study from American researchers suggests that exposure to bisphenol A (BPA) may play a role in these neurodevelopmental conditions. While preliminary, the findings could significantly impact our understanding of these disorders and inform public health practices.
BPA, a chemical widely used in the production of plastics, is a pervasive presence in modern life. It’s found in everyday items such as food packaging, plastic bottles, the interior linings of canned goods, and even some children’s toys. This widespread exposure is raising concerns, particularly as previous research has linked BPA to various health problems, including hormonal disruptions that can affect fertility and potentially increase the risk of certain cancers, like breast cancer.
A common substance in plastic may be linked to autism and ADHD. © gevende, iStock
The study, conducted jointly by Rowan University and Rutgers University, revealed a significant difference in how children with autism or ADHD eliminate BPA from their bodies. Researchers, whose work was published in PLOS one, examined the process of glucuronidation – a crucial mechanism the body uses to remove toxins from the blood through urine.
The results showed that children with autism had an approximately 11% reduction in BPA elimination efficiency, while those with ADHD experienced a 17% reduction, compared to a control group of neurotypical children. This suggests a prolonged exposure to the toxic effects of BPA in these children, potentially due to genetic variations affecting the elimination process. Understanding these variations could be key to developing targeted interventions.
The increased persistence of BPA in children with autism and ADHD raises important questions about its potential impact on neurological development and function. While the study doesn’t establish a direct causal link between BPA exposure and these disorders, it offers a compelling avenue for exploring the complex interplay between genetic and environmental factors in their development.
|
Group |
Reduction in BPA elimination efficiency |
|
Children with autism |
11% |
|
Children with ADHD |
17% |
|
Neurotypical children |
0% (reference group) |
This research adds to a growing body of work investigating the connections between environmental pollutants and neurodevelopmental disorders. Researchers emphasize that the effect of BPA must be substantial to be detected in a study of moderate size, suggesting its potential significance.
Notably, not all children with autism or ADHD exhibited difficulties eliminating BPA, highlighting the multifactorial nature of these conditions. Further research is needed to clarify the precise mechanisms by which BPA might influence neurological development, both during pregnancy and later in a child’s life.
Given these findings, limiting BPA exposure, particularly in vulnerable populations, appears prudent. Safer alternatives to BPA-containing plastics are available and could be prioritized. As research progresses, this study serves as a reminder of the importance of considering the impact of our chemical environment on the neurodevelopmental health of children.
