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‘World’s most contagious disease’ on track for highest US cases in 35 years

U.S. measles cases have surpassed 2,100 in 2026, threatening the nation's measles-free status as health experts track the largest outbreak in decades.

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The obvious questions

How many measles cases have been reported in the U.S. in 2026?

Coverage indicates that cases have surpassed 2,100.

Is the Spartanburg measles outbreak still active?

According to Medical Daily, the 997-case outbreak in Spartanburg, South Carolina, has ended.

What is the status of U.S. measles elimination?

Reports suggest the U.S. could lose its measles-free status by November 2026, with some experts noting that elimination has effectively been lost in substance.

The story so far

Measles infections in the United States have reached a 35-year high, with reported cases exceeding 2,100 this year. While a localized outbreak in Spartanburg, South Carolina, is showing signs of slowing and has concluded, the broader national trajectory indicates that elimination status is under significant pressure.

Coverage from outlets including AOL.com, Medical Daily, and the New York Post emphasizes the rapid spread of the disease within vaccine-hesitant communities. Drug Topics notes that the total number of cases surpassed 2,000, while Gastroenterology & Endoscopy News has issued specific clinical guidance for healthcare providers in response to the trend.

Observers are watching to see if the U.S. will officially lose its measles-free status by November 2026. Ongoing developments include the pursuit of new treatment options, such as those currently under development by a New Haven-based biotech firm.

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