Melatonin Use and Heart Failure Risk: New Study Raises Questions

Preliminary research presented today suggests a possible link between long-term melatonin use and an increased risk of heart failure, though experts caution against immediate alarm.

The study, presented at an American Heart Association meeting, tracked adults diagnosed with insomnia who were prescribed melatonin for at least a year. Researchers found that 4.6% of chronic melatonin users developed heart failure over five years, compared to 2.7% of insomnia patients who did not use the supplement. It’s important to note this research has not yet undergone peer review. This finding comes as more Americans than ever are turning to sleep aids to combat rising stress and sleep disorders.

Cardiologists emphasize that this type of observational study cannot prove melatonin causes heart failure, and the insomnia itself may be a contributing factor. “We should not raise the alarm and tell patients to stop taking all their melatonin,” said Dr. Pratik Sandesara of Emory Healthcare, who was not involved in the research. The body naturally produces melatonin to regulate sleep cycles, and supplemental use is common for sleep issues or jet lag. For more information on sleep disorders, visit the Sleep Foundation.

Researchers also pointed out limitations, including the fact that melatonin is available over-the-counter in the U.S., meaning usage may not be accurately reflected in prescription records. Additionally, supplement quality and dosages vary widely. Dr. Clyde Yancy of Northwestern University noted that while the study doesn’t prove harm, there’s also no evidence supporting indefinite melatonin use, and practicing good sleep hygiene is crucial. Officials recommend patients discuss melatonin use with their doctors.

Further research is needed to fully understand the potential risks and benefits of long-term melatonin supplementation, and experts advise a cautious approach.