Jakarta, Indonesia – As many as one in ten women of reproductive age grapple with polycystic ovary syndrome (PCOS), a hormonal disorder frequently linked to infertility. A recent discussion with Dr. Niken Pudji pangastuti, a specialist in obstetrics, gynecology, fertility, endocrinology, and reproduction, highlighted the complexities of PCOS and its impact on a woman’s ability to conceive, noting that accomplished treatment isn’t always straightforward and can vary significantly between patients. This report details the challenges and nuances of PCOS, as discussed at a recent Extensive Obgyn Service event in South jakarta on December 13, 2025.
JAKARTA, KOMPAS.com – Polycystic ovary syndrome (PCOS) is often linked to difficulties women face when trying to conceive. Understanding the connection between PCOS and fertility is crucial for women planning families and for healthcare providers offering reproductive health services.
Many women with PCOS worry about their chances of becoming pregnant, sometimes even before they begin trying. But is it accurate to say that PCOS always makes it harder for a woman to have a child?
According to Dr. Niken Pudji Pangastuti, SpOG KFER, a specialist in obstetrics and gynecology with subspecialties in fertility, endocrinology, and reproduction, PCOS is closely associated with infertility, primarily due to issues with egg development.
“That’s correct, because PCOS is a condition involving disruptions in the egg maturation process. To achieve pregnancy, a patient needs a mature egg and healthy sperm,” she explained during the Comprehensive Obgyn Service event at Brawijaya Hospital Antasari in South Jakarta on Saturday, December 13, 2025.
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Ovulatory Dysfunction is a Primary Challenge
One of the main challenges associated with PCOS, Dr. Niken explained, is irregular or absent ovulation. Normally, an egg matures and is released each menstrual cycle. However, in women with PCOS, this process doesn’t always occur as it should.
“If the egg doesn’t mature, ovulation may not happen at all, making conception difficult,” she clarified.
When ovulation is infrequent or doesn’t occur, the opportunity for fertilization is reduced. This often means women with PCOS may take longer to get pregnant or require medical assistance to conceive.
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Multiple Factors Contribute to PCOS Development
PCOS is a relatively common condition affecting women of reproductive age. Its causes are complex and multifaceted.
“PCOS is frequently seen, and can be linked to lifestyle factors, diet, lack of rest, or other influences like genetics,” Dr. Niken noted.
This combination of lifestyle and genetic factors means PCOS presents differently in each patient, varying in symptoms, severity, and response to treatment. Understanding these individual variations is key to effective management.
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PCOS Treatment Can Be Complex
Dr. Niken emphasized that managing PCOS isn’t always straightforward, and patient responses to therapy can vary significantly.
“Treatment isn’t as simple as with other fertility issues. Some cases of PCOS can be helped with fertility drugs, but others are resistant to any medication,” she said.
When fertility drugs are ineffective, it presents a challenge in the field of reproductive medicine.
“These are the cases that become a dilemma in fertility treatment, because despite trying various fertility drugs, they don’t work. Then, attempting injections can sometimes be excessive,” Dr. Niken explained.
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